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RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF.
Tsuchiya, Motohiro; Kalurupalle, Swathi; Kumar, Parameet; Ghoshal, Sarani; Zhang, Yongqing; Lehrmann, Elin; Becker, Kevin G; Gorospe, Myriam; Biswas, Roopa.
Afiliação
  • Tsuchiya M; a Molecular and Cell Biology Program, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.
  • Kalurupalle S; b Department of Anatomy , Physiology and Genetics, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.
  • Kumar P; b Department of Anatomy , Physiology and Genetics, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.
  • Ghoshal S; b Department of Anatomy , Physiology and Genetics, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.
  • Zhang Y; b Department of Anatomy , Physiology and Genetics, Uniformed Services University of the Health Sciences , Bethesda , MD , USA.
  • Lehrmann E; c Laboratory of Genetics, National Institute on Aging, National Institutes of Health , Baltimore , MD , USA.
  • Becker KG; c Laboratory of Genetics, National Institute on Aging, National Institutes of Health , Baltimore , MD , USA.
  • Gorospe M; c Laboratory of Genetics, National Institute on Aging, National Institutes of Health , Baltimore , MD , USA.
  • Biswas R; c Laboratory of Genetics, National Institute on Aging, National Institutes of Health , Baltimore , MD , USA.
RNA Biol ; 13(9): 837-47, 2016 09.
Article em En | MEDLINE | ID: mdl-27284727
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Mucosa Respiratória / Fibrose Cística / MicroRNAs / Proteínas Adaptadoras de Transdução de Sinal / Fator de Crescimento do Tecido Conjuntivo / Pulmão Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Mucosa Respiratória / Fibrose Cística / MicroRNAs / Proteínas Adaptadoras de Transdução de Sinal / Fator de Crescimento do Tecido Conjuntivo / Pulmão Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article