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Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial.
Bijlsma, Johannes W J; Welsing, Paco M J; Woodworth, Thasia G; Middelink, Leonie M; Pethö-Schramm, Attila; Bernasconi, Corrado; Borm, Michelle E A; Wortel, Cornelis H; Ter Borg, Evert Jan; Jahangier, Z Nazira; van der Laan, Willemijn H; Bruyn, George A W; Baudoin, Paul; Wijngaarden, Siska; Vos, Petra A J M; Bos, Reinhard; Starmans, Mirian J F; Griep, Eduard N; Griep-Wentink, Joanna R M; Allaart, Cornelia F; Heurkens, Anton H M; Teitsma, Xavier M; Tekstra, Janneke; Marijnissen, Anne Carien A; Lafeber, Floris P J; Jacobs, Johannes W G.
Afiliação
  • Bijlsma JWJ; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Welsing PMJ; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Woodworth TG; Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
  • Middelink LM; Middelinc, Utrecht, Netherlands.
  • Pethö-Schramm A; Pharmaceuticals Division, F Hoffmann-La Roche, Basel, Switzerland.
  • Bernasconi C; Pharmaceuticals Division, F Hoffmann-La Roche, Basel, Switzerland.
  • Borm MEA; Roche Nederland BV, Woerden, Netherlands.
  • Wortel CH; Accelovance, Hudson, MA, USA.
  • Ter Borg EJ; Sint Antonius Ziekenhuis, Nieuwegein, Netherlands.
  • Jahangier ZN; Tergooiziekenhuizen, Hilversum, Netherlands.
  • van der Laan WH; Maartenskliniek Woerden, Woerden, Netherlands.
  • Bruyn GAW; MC Groep, Lelystad, Netherlands.
  • Baudoin P; MC Groep, Lelystad, Netherlands.
  • Wijngaarden S; Gelre Ziekenhuizen Apeldoorn, Apeldoorn, Netherlands.
  • Vos PAJM; Amphia Ziekenhuis, Breda, Netherlands.
  • Bos R; Medical Center Leeuwarden, Leeuwarden, Netherlands.
  • Starmans MJF; Zuyderland Atrium-Orbis Heerlen, Heerlen, Netherlands.
  • Griep EN; Antonius Ziekenhuis Sneek, Sneek, Netherlands.
  • Griep-Wentink JRM; Antonius Ziekenhuis Sneek, Sneek, Netherlands.
  • Allaart CF; Leids Universitair Medisch Centrum, Leiden, Netherlands.
  • Heurkens AHM; Meander Medisch Centrum, Amersfoort, Netherlands.
  • Teitsma XM; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Tekstra J; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Marijnissen ACA; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Lafeber FPJ; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands.
  • Jacobs JWG; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address: j.w.g.jacobs@umcutrecht.nl.
Lancet ; 388(10042): 343-355, 2016 Jul 23.
Article em En | MEDLINE | ID: mdl-27287832
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Metotrexato / Antirreumáticos / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials / Etiology_studies / Guideline Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Metotrexato / Antirreumáticos / Anticorpos Monoclonais Humanizados Tipo de estudo: Clinical_trials / Etiology_studies / Guideline Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article