Advances in the synthesis of α-quaternary α-ethynyl α-amino acids.
Amino Acids
; 48(9): 2081-101, 2016 09.
Article
em En
| MEDLINE
| ID: mdl-27312093
ABSTRACT
α-Quaternary α-ethynyl α-amino acids are an important class of non-proteinogenic amino acids that play an important role in the development of peptides and peptidomimetics as therapeutic agents and in the inhibition of enzyme activities. This review provides an overview of the literature concerning synthesis and applications of α-quaternary α-ethynyl α-amino acids covering the period from 1977 to 2015.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Aminoácidos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article