Four new tetracyclic alkaloids with cis-decahydroquinoline motif from Myrioneuron effusum.
Fitoterapia
; 112: 217-21, 2016 Jul.
Article
em En
| MEDLINE
| ID: mdl-27316979
ABSTRACT
Four new Myrioneuron alkaloids, mysumamides A-D (1-4), along with three known ones were isolated from the twigs and leaves of Myrioneuron effusum. All of these alkaloids possessed the tetracyclic skeleton and contained the decahydroquinoline (cis-DHQ) moiety. Their structures and relative configurations were elucidated on the basis of spectroscopic methods, especially 2D NMR techniques. The absolute configuration of 1 was determined by single-crystal X-ray diffraction. The cytotoxic activities of these compounds were also evaluated in vitro.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinolinas
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Rubiaceae
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Alcaloides
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article