Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models.

Nuvoli, Barbara; Sacconi, Andrea; Cortese, Giancarlo; Germoni, Sabrina; Murer, Bruno; Galati, Rossella

Nuvoli, Barbara; Sacconi, Andrea; Cortese, Giancarlo; Germoni, Sabrina; Murer, Bruno; Galati, Rossella.

Afiliação

Nuvoli B; Preclinical Models and New Therapeutic Agent Unit, Regina Elena National Cancer Institute, Rome, Italy.
Sacconi A; Oncogenomic and Epigenetic Unit, Regina Elena National Cancer Institute, Rome, Italy.
Cortese G; SAFU Unit, Regina Elena National Cancer Institute, Rome, Italy.
Germoni S; SAFU Unit, Regina Elena National Cancer Institute, Rome, Italy.
Murer B; Department of Anatomic Pathology, Mestre Hospital, Venezia, Italy.
Galati R; Preclinical Models and New Therapeutic Agent Unit, Regina Elena National Cancer Institute, Rome, Italy.

Oncotarget ; 7(30): 47116-47126, 2016 Jul 26.

Article em En | MEDLINE | ID: mdl-27323398

Assuntos

Estradiol/metabolismo; Mesotelioma/metabolismo; Neoplasias Pleurais/metabolismo; Idoso; Animais; Linhagem Celular Tumoral; Feminino; Humanos; Imuno-Histoquímica; Masculino; Mesotelioma/patologia; Camundongos; Neoplasias Pleurais/patologia

Palavras-chave

GPR30; estradiol; estrogen receptor α; estrogen receptor ß; mesothelioma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pleurais / Estradiol / Mesotelioma Limite: Aged / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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