Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development.

Clay, Hilary; Wilsbacher, Lisa D; Wilson, Stephen J; Duong, Daniel N; McDonald, Maayan; Lam, Ian; Park, Kitae Eric; Chun, Jerold; Coughlin, Shaun R

Clay, Hilary; Wilsbacher, Lisa D; Wilson, Stephen J; Duong, Daniel N; McDonald, Maayan; Lam, Ian; Park, Kitae Eric; Chun, Jerold; Coughlin, Shaun R.

Afiliação

Clay H; Cardiovascular Research Institute, University of California, San Francisco, United States.
Wilsbacher LD; Cardiovascular Research Institute, University of California, San Francisco, United States; Department of Medicine, University of California, San Francisco, United States.
Wilson SJ; Cardiovascular Research Institute, University of California, San Francisco, United States.
Duong DN; Cardiovascular Research Institute, University of California, San Francisco, United States.
McDonald M; Cardiovascular Research Institute, University of California, San Francisco, United States.
Lam I; Cardiovascular Research Institute, University of California, San Francisco, United States.
Park KE; Department of Medicine and Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, United States.
Chun J; Department of Molecular and Cellular Neuroscience, Dorris Neuroscience Center, The Scripps Research Institute, United States.
Coughlin SR; Cardiovascular Research Institute, University of California, San Francisco, United States; Department of Medicine, University of California, San Francisco, United States. Electronic address: Shaun.Coughlin@UCSF.edu.

Dev Biol ; 418(1): 157-165, 2016 10 01.

Article em En | MEDLINE | ID: mdl-27333774

Assuntos

Coração/embriologia; Miocárdio/metabolismo; Miócitos Cardíacos/metabolismo; Receptores de Lisoesfingolipídeo/genética; Receptores de Lisoesfingolipídeo/metabolismo; Animais; Proliferação de Células/genética; Técnicas de Inativação de Genes; Comunicação Interventricular/genética; Camundongos; Camundongos Transgênicos; Miócitos Cardíacos/citologia; Miofibrilas/genética; Miofibrilas/metabolismo; Cadeias Leves de Miosina/genética; Transdução de Sinais; Receptores de Esfingosina-1-Fosfato

Palavras-chave

Cardiomyocyte; GPCR; Heart development; Noncompaction; S1P1; S1pr1; Sphingosine 1-phosphate; Sphingosine 1-phosphate receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Miócitos Cardíacos / Receptores de Lisoesfingolipídeo / Coração / Miocárdio Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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