Adeninealkylresorcinol, the first alkylresorcinol tethered with nucleobase from Lasiodiplodia sp.
Fitoterapia
; 112: 254-9, 2016 Jul.
Article
em En
| MEDLINE
| ID: mdl-27343368
ABSTRACT
Adeninealkylresorcinol (1), an unusual alkylresorcinol with adenine-alkylresorcinol conjoined skeleton, was isolated from an endophytic fungus Lasiodiplodia sp. obtained from a traditional Chinese medicine Houttuynia cordata Thunb., together with three new biogenetically related compounds (2-4). Their structures were elucidated by comprehensive spectroscopic analysis, and the absolute configuration of 4 was determined by the modified Mosher's method and quantum chemical calculation. Among them, adeninealkylresorcinol (1) is the first alkylresorcinol tethered with nucleobase. In addition, the antioxidant, cytotoxic, and antimicrobial activities of 1-3 were evaluated.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ascomicetos
/
Resorcinóis
/
Adenina
/
Houttuynia
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article