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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ASP2408, a Potent Selective T-Cell Costimulation Modulator After Single and Multiple Ascending Doses in Healthy Volunteers and RA Patients.
Zhu, Tong; Keirns, James; Howieson, Corrie; Kaibara, Atsunori; Goldwater, Ronald; Kivitz, Alan J; Chindalore, Vishala; Cohen, Stanley; Santos, Vicki; Akinlade, Bolanle; Kernstock, Robert; Delgado-Herrera, Leticia; Blahunka, Paul C; Karrer, Erik E; Garg, Jay P; Samberg, Nancy; Zeiher, Bernhardt G.
Afiliação
  • Zhu T; Astellas Pharma Global Development, Northbrook, IL, USA. tong.zhu@astellas.com.
  • Keirns J; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Howieson C; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Kaibara A; Astellas Pharma, Inc, Tokyo, Japan.
  • Goldwater R; PAREXEL, Baltimore, MD, USA.
  • Kivitz AJ; Altoona Center for Clinical Research, Duncansville, PA, USA.
  • Chindalore V; Pinnacle Research Group/Anniston Medical Clinic, Anniston, AL, USA.
  • Cohen S; Metroplex Clinical Research Center, Dallas, TX, USA.
  • Santos V; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Akinlade B; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Kernstock R; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Delgado-Herrera L; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Blahunka PC; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Karrer EE; Astellas Drug Discovery Research, Northbrook, IL, USA.
  • Garg JP; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Samberg N; Astellas Pharma Global Development, Northbrook, IL, USA.
  • Zeiher BG; Astellas Pharma Global Development, Northbrook, IL, USA.
Clin Pharmacol Drug Dev ; 5(5): 408-25, 2016 Sep.
Article em En | MEDLINE | ID: mdl-27410490
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Imunoglobulina G / Linfócitos T / Imunoconjugados / Antirreumáticos / Antígeno CTLA-4 Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Imunoglobulina G / Linfócitos T / Imunoconjugados / Antirreumáticos / Antígeno CTLA-4 Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article