Effects of yogurt containing Lactobacillus plantarum HOKKAIDO on immune function and stress markers.
J Tradit Complement Med
; 6(3): 275-80, 2016 Jul.
Article
em En
| MEDLINE
| ID: mdl-27419093
Lactobacillus plantarum HOKKAIDO (HOKKAIDO strain) was isolated from well-pickled vegetables in Hokkaido, Japan. We report a randomized, double-blind, placebo-controlled study evaluating the effects of L. plantarum HOKKAIDO on immune function and stress markers in 171 adult subjects. Subjects were divided into three groups: the L. plantarum HOKKAIDO yogurt group, the placebo-1 group who ingested yogurt without the HOKKAIDO strain, and the placebo-2 group who ingested a yogurt-like dessert without the HOKKAIDO strain. Hematological tests and body composition measurements were performed before and after 4 and 8 weeks of blinded ingestion. Although no significant differences in natural killer cell activity were observed, it was found that neutrophil ratio significantly decreased and lymphocytes tended to increase in the HOKKAIDO strain yogurt group compared with the yogurt-like dessert group. In addition, the neutrophil-to-lymphocyte ratio, a stress marker, tended to improve in the HOKKAIDO strain yogurt group compared with the yogurt-like dessert group. These results suggest that the ingestion of HOKKAIDO strain yogurt tends to improve immune activity and decrease stress markers.
BMI, body mass index; BW, body weight; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; HPA, hypothalamic-pituitary-adrenal; HbA1c, hemoglobin A1c; Immune activity; LDL-C, low-density lipoprotein cholesterol; Lactobacillus plantarum HOKKAIDO; NK, natural killer; NLR, neutrophil-to-lymphocyte ratio; Natural killer cell; Neutrophil-to-lymphocyte ratio; Stress markers; TC, total cholesterol; TG, triglyceride
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Base de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article