Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor-Î³ coactivator-1&#945;-dependent vitamin D receptor pathway.

Feigerlova, Eva; Demarquet, Lea; Melhem, Hassan; Ghemrawi, Rose; Battaglia-Hsu, Shyue-Fang; Ewu, Essi; Alberto, Jean-Marc; Helle, Deborah; Weryha, Georges; Guéant, Jean-Louis

Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor-Î³ coactivator-1α-dependent vitamin D receptor pathway.

Feigerlova, Eva; Demarquet, Lea; Melhem, Hassan; Ghemrawi, Rose; Battaglia-Hsu, Shyue-Fang; Ewu, Essi; Alberto, Jean-Marc; Helle, Deborah; Weryha, Georges; Guéant, Jean-Louis.

Afiliação

Feigerlova E; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France; Division of Endocrinology, Regional University Hospital Center of Nancy, VandÅuvre les Nancy, France eva.feigerlova@chu-poitiers.fr.
Demarquet L; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Melhem H; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Ghemrawi R; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Battaglia-Hsu SF; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Ewu E; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Alberto JM; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Helle D; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France.
Weryha G; Division of Endocrinology, Regional University Hospital Center of Nancy, VandÅuvre les Nancy, France.
Guéant JL; INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, VandÅuvre les Nancy, France; jean-louis.gueant@medecine.uhp-nancy.fr.

FASEB J ; 30(10): 3598-3612, 2016 10.

Article em En | MEDLINE | ID: mdl-27435264

Assuntos

Desenvolvimento Ósseo/fisiologia; PPAR gama/metabolismo; Receptores de Calcitriol/metabolismo; Animais; Calcitriol/metabolismo; Linhagem Celular Tumoral; Feminino; Proteínas de Choque Térmico/metabolismo; Humanos; Ratos; Receptores de Estrogênio/metabolismo; Transdução de Sinais/efeitos dos fármacos; Receptor ERRalfa Relacionado ao Estrogênio

Palavras-chave

1,25-dihydroxyvitamin D3; bone development; folate; osteoblast differentiation; vitamin B12

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Base de dados: MEDLINE Assunto principal: Desenvolvimento Ósseo / Receptores de Calcitriol / PPAR gama Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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