Metabolic profiles of the Flos Abelmoschus manihot extract by intestinal bacteria from the normal and CKD model rats based on UPLC-Q-TOF/MS.

Du, Le-Yue; Tao, Jin-Hua; Jiang, Shu; Qian, Da-Wei; Guo, Jian-Ming; Duan, Jin-Ao

Du, Le-Yue; Tao, Jin-Hua; Jiang, Shu; Qian, Da-Wei; Guo, Jian-Ming; Duan, Jin-Ao.

Afiliação

Du LY; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.
Tao JH; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.
Jiang S; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.
Qian DW; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.
Guo JM; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.
Duan JA; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, People's Republic of China.

Biomed Chromatogr ; 31(2)2017 Feb.

Article em En | MEDLINE | ID: mdl-27451133

Assuntos

Medicamentos de Ervas Chinesas/química; Medicamentos de Ervas Chinesas/metabolismo; Intestinos/microbiologia; Insuficiência Renal Crônica/microbiologia; Abelmoschus; Animais; Cromatografia Líquida de Alta Pressão/métodos; Flavonoides/análise; Flavonoides/metabolismo; Mucosa Intestinal/metabolismo; Masculino; Malvaceae/química; Espectrometria de Massas/métodos; Metaboloma; Quercetina/análise; Quercetina/metabolismo; Ratos; Ratos Sprague-Dawley; Insuficiência Renal Crônica/metabolismo

Palavras-chave

Flos Abelmoschus manihot; UPLC-Q-TOF/MS; chronic kidney disease; gut microbiome; metabolism; methylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Insuficiência Renal Crônica / Intestinos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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