Continuing efforts to standardize measured serum growth hormone values in Japan.
Endocr J
; 63(10): 933-936, 2016 Oct 29.
Article
em En
| MEDLINE
| ID: mdl-27452373
ABSTRACT
Determination of serum growth hormone (GH) levels is mandatory for diagnosis of GH deficiency and excess. In the present study, we, the Study Committee for GH and Its Related Factors, The Foundation for Growth Science, Japan measured GH values in serum samples using all the commercially available kits in Japan. Significant discrepancies in the GH values were observed among the kits in spite of using the unified recombinant human GH-based standards. To deal with the discrepancies, we established a formula using a linear structural relationship model and were able to standardize the GH values. We propose to use the formula to diagnose GH deficiency and excess in Japan.
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Base de dados:
MEDLINE
Assunto principal:
Hormônio do Crescimento Humano
/
Técnicas de Diagnóstico Endócrino
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limite:
Adult
/
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article