Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate cardiometabolic risk factors.

Babish, John G; Dahlberg, Clinton J; Ou, Joseph J; Keller, William J; Gao, Wei; Kaadige, Mohan R; Brabazon, Holly; Lamb, Joseph; Soudah, Hani C; Kou, Xiaolan; Zhang, Zhe; Pacioretty, Linda M; Tripp, Matthew L

Babish, John G; Dahlberg, Clinton J; Ou, Joseph J; Keller, William J; Gao, Wei; Kaadige, Mohan R; Brabazon, Holly; Lamb, Joseph; Soudah, Hani C; Kou, Xiaolan; Zhang, Zhe; Pacioretty, Linda M; Tripp, Matthew L.

Afiliação

Babish JG; a Bionexus, Ltd., 53 Brown Road, Suite B, Ithaca, NY 14850, USA.
Dahlberg CJ; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Ou JJ; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Keller WJ; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Gao W; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Kaadige MR; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Brabazon H; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Lamb J; b Hughes Center for Research and Innovation, Nature's Sunshine Products, 2500 Executive Parkway, Lehi, UT 84043, USA.
Soudah HC; d Premier Medical Specialists, Stella Maris Obesity Medicine, Tenet Healthcare System, 2315 Dougherty Ferry Rd., Suite 109, St. Louis, MO 63122, USA.
Kou X; e Washington University School of Medicine, St. Louis, 660 S Euclid Ave, St. Louis, MO 63110, USA.
Zhang Z; c Nature's Sunshine Products, 1655 North Main St., Spanish Fork, UT 84660, USA.
Pacioretty LM; c Nature's Sunshine Products, 1655 North Main St., Spanish Fork, UT 84660, USA.
Tripp ML; a Bionexus, Ltd., 53 Brown Road, Suite B, Ithaca, NY 14850, USA.

Can J Physiol Pharmacol ; 94(12): 1257-1266, 2016 Dec.

Article em En | MEDLINE | ID: mdl-27463949

Assuntos

Antioxidantes/uso terapêutico; Citrus; Dislipidemias/tratamento farmacológico; Doenças Metabólicas/prevenção & controle; Compostos Fitoquímicos/uso terapêutico; Extratos Vegetais/uso terapêutico; Adulto; Idoso; Antioxidantes/química; Antioxidantes/isolamento & purificação; Composição de Medicamentos; Sinergismo Farmacológico; Dislipidemias/diagnóstico; Dislipidemias/metabolismo; Feminino; Humanos; Masculino; Doenças Metabólicas/metabolismo; Pessoa de Meia-Idade; Compostos Fitoquímicos/química; Compostos Fitoquímicos/isolamento & purificação; Projetos Piloto; Extratos Vegetais/isolamento & purificação; Extratos Vegetais/farmacologia; Fatores de Risco

Palavras-chave

HbA1c; LDL oxydées; antioxidant; antioxydant; bergamot; bergamote; cardiometabolic disease; dyslipidemia; dyslipidémie; maladie cardiométabolique; myeloperoxidase; myéloperoxydase; oxidized LDL

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Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Citrus / Dislipidemias / Compostos Fitoquímicos / Doenças Metabólicas / Antioxidantes Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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