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Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo.
Branco, Vania G; Iqbal, Asif; Alvarez-Flores, Miryam P; Sciani, Juliana M; de Andrade, Sonia A; Iwai, Leo K; Serrano, Solange M T; Chudzinski-Tavassi, Ana M.
Afiliação
  • Branco VG; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil.
  • Iqbal A; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil; Centre of Excellence for New Target Discovery (CENTD), Butantan Institute, São Paulo, SP, Brazil.
  • Alvarez-Flores MP; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil; Centre of Excellence for New Target Discovery (CENTD), Butantan Institute, São Paulo, SP, Brazil.
  • Sciani JM; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil.
  • de Andrade SA; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil.
  • Iwai LK; Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, SP, Brazil.
  • Serrano SM; Special Laboratory of Applied Toxinology, Butantan Institute, São Paulo, SP, Brazil.
  • Chudzinski-Tavassi AM; Laboratory of Biochemistry and Biophysics, Butantan Institute, Sao Paulo, SP, Brazil; Centre of Excellence for New Target Discovery (CENTD), Butantan Institute, São Paulo, SP, Brazil. Electronic address: ana.chudzinski@butantan.gov.br.
Biochim Biophys Acta ; 1864(10): 1428-35, 2016 10.
Article em En | MEDLINE | ID: mdl-27479486
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas e Peptídeos Salivares / Coagulação Sanguínea / Fator Xa / Inibidores do Fator Xa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas e Peptídeos Salivares / Coagulação Sanguínea / Fator Xa / Inibidores do Fator Xa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article