Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase &#954; and Mutagenic Bypass by DNA Polymerases Î·, Î¶, and Rev1.

Bose, Arindam; Millsap, Amy D; DeLeon, Arnie; Rizzo, Carmelo J; Basu, Ashis K

Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases Î·, Î¶, and Rev1.

Bose, Arindam; Millsap, Amy D; DeLeon, Arnie; Rizzo, Carmelo J; Basu, Ashis K.

Afiliação

Bose A; Department of Chemistry, University of Connecticut , Storrs, Connecticut 06269, United States.
Millsap AD; Department of Chemistry, Vanderbilt University , Nashville, Tennessee 37232, United States.
DeLeon A; Department of Chemistry, Vanderbilt University , Nashville, Tennessee 37232, United States.
Rizzo CJ; Department of Chemistry, Vanderbilt University , Nashville, Tennessee 37232, United States.
Basu AK; Department of Chemistry, University of Connecticut , Storrs, Connecticut 06269, United States.

Chem Res Toxicol ; 29(9): 1549-59, 2016 09 19.

Article em En | MEDLINE | ID: mdl-27490094

Assuntos

Adutos de DNA/biossíntese; DNA Polimerase Dirigida por DNA/metabolismo; Dieta; Proteínas Nucleares/metabolismo; Nucleotidiltransferases/metabolismo; Adutos de DNA/química; Adutos de DNA/genética; Replicação do DNA/efeitos dos fármacos; Desoxiguanosina/biossíntese; Células HEK293; Humanos; Imidazóis/toxicidade; Isoleucina/análogos & derivados; Isoleucina/toxicidade; Estrutura Molecular; Mutagênicos/toxicidade; Quinoxalinas/toxicidade; DNA Polimerase iota

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Adutos de DNA / Dieta / DNA Polimerase Dirigida por DNA / Nucleotidiltransferases Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google