Copper-Catalyzed Oxirane-Opening Reaction with Aryl Iodides and Se Powder.
J Org Chem
; 81(17): 7584-90, 2016 09 02.
Article
em En
| MEDLINE
| ID: mdl-27490248
ABSTRACT
Using Se powder as the selenating reagent, the copper-catalyzed double C-Se cross-coupling of aryl iodides, epoxides, and elemental selenium has been developed. This strategy provides a straightforward approach to the synthesis of ß-hydroxy phenylselenides with excellent regioselectivity of the ring opening reaction. This process proceeds in generally good yields and is compatible with a broad range of functional groups.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article