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N-pentyl-nitrofurantoin induces apoptosis in HL-60 leukemia cell line by upregulating BAX and downregulating BCL-xL gene expression.
Andrade, Jeyce K F; Souza, Márcia I F; Gomes Filho, Manoel A; Silva, Diogo M F; Barros, André L S; Rodrigues, Maria D; Silva, Paulo B N; Nascimento, Silene C; Aguiar, Jaciana S; Brondani, Dalci J; Militão, Gardênia C G; Silva, Teresinha G.
Afiliação
  • Andrade JK; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil.
  • Souza MI; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Pernambuco, Brazil.
  • Gomes Filho MA; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Pernambuco, Brazil.
  • Silva DM; Department of Morphology and Animal Physiology, Federal Rural University of Pernambuco, Pernambuco, Brazil.
  • Barros AL; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil.
  • Rodrigues MD; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil.
  • Silva PB; Department of Physiology and Pharmacology, Federal University of Pernambuco, Pernambuco, Brazil.
  • Nascimento SC; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil.
  • Aguiar JS; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil.
  • Brondani DJ; Department of Pharmaceutical Sciences, Federal University of Pernambuco, Pernambuco, Brazil.
  • Militão GC; Department of Physiology and Pharmacology, Federal University of Pernambuco, Pernambuco, Brazil.
  • Silva TG; Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil. Electronic address: teresinha.goncalves@pq.cnpq.br.
Pharmacol Rep ; 68(5): 1046-53, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27505854
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Expressão Gênica / Regulação para Cima / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína X Associada a bcl-2 / Nitrofurantoína Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Expressão Gênica / Regulação para Cima / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína X Associada a bcl-2 / Nitrofurantoína Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article