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Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma.
Carita, Guillaume; Frisch-Dit-Leitz, Estelle; Dahmani, Ahmed; Raymondie, Chloé; Cassoux, Nathalie; Piperno-Neumann, Sophie; Némati, Fariba; Laurent, Cécile; De Koning, Leanne; Halilovic, Ensar; Jeay, Sebastien; Wylie, Andrew; Emery, Caroline; Roman-Roman, Sergio; Schoumacher, Marie; Decaudin, Didier.
Afiliação
  • Carita G; Laboratory of Preclinical Investigation, Department of Translational Research, PSL University, Institut Curie, Paris, France.
  • Frisch-Dit-Leitz E; Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Dahmani A; Laboratory of Preclinical Investigation, Department of Translational Research, PSL University, Institut Curie, Paris, France.
  • Raymondie C; Laboratory of Preclinical Investigation, Department of Translational Research, PSL University, Institut Curie, Paris, France.
  • Cassoux N; Department of Ophthalmological Oncology, Institut Curie, Paris, France.
  • Piperno-Neumann S; Department of Medical Oncology, Institut Curie, Paris, France.
  • Némati F; Laboratory of Preclinical Investigation, Department of Translational Research, PSL University, Institut Curie, Paris, France.
  • Laurent C; Residual Tumor & Response to Treatment Laboratory, Department of Translational Research, Institut Curie, PSL University, Paris, Paris, France.
  • De Koning L; RPPA Platform, Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Halilovic E; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Jeay S; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Wylie A; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Emery C; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Roman-Roman S; Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Schoumacher M; Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Decaudin D; Laboratory of Preclinical Investigation, Department of Translational Research, PSL University, Institut Curie, Paris, France.
Oncotarget ; 7(23): 33542-56, 2016 Jun 07.
Article em En | MEDLINE | ID: mdl-27507190
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Protocolos de Quimioterapia Combinada Antineoplásica / Melanoma Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Uveais / Protocolos de Quimioterapia Combinada Antineoplásica / Melanoma Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article