Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo.

Levitte, Steven; Adams, Kristin N; Berg, Russell D; Cosma, Christine L; Urdahl, Kevin B; Ramakrishnan, Lalita

Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo.

Levitte, Steven; Adams, Kristin N; Berg, Russell D; Cosma, Christine L; Urdahl, Kevin B; Ramakrishnan, Lalita.

Afiliação

Levitte S; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK; Molecular and Cellular Biology Graduate Program and Medical Scientist Training Program, University of Washington, Seattle, USA.
Adams KN; Center for Infectious Disease Research, Seattle, WA 98195, USA; Department of Pediatrics, University of Washington, Seattle, WA 98109, USA.
Berg RD; Molecular and Cellular Biology Graduate Program and Medical Scientist Training Program, University of Washington, Seattle, USA.
Cosma CL; Department of Microbiology, University of Washington, Seattle, WA 98109, USA.
Urdahl KB; Center for Infectious Disease Research, Seattle, WA 98195, USA; Department of Immunology, University of Washington, Seattle, WA 98109, USA.
Ramakrishnan L; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. Electronic address: lr404@cam.ac.uk.

Cell Host Microbe ; 20(2): 250-8, 2016 Aug 10.

Article em En | MEDLINE | ID: mdl-27512905

Assuntos

Antibacterianos/metabolismo; Ácidos Carboxílicos/metabolismo; Lisossomos/microbiologia; Macrófagos/microbiologia; Viabilidade Microbiana/efeitos dos fármacos; Mycobacterium marinum/fisiologia; Estresse Fisiológico; Animais; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Células Cultivadas; Modelos Animais de Doenças; Interações Hospedeiro-Patógeno; Camundongos Endogâmicos C57BL; Infecções por Mycobacterium não Tuberculosas/microbiologia; Mycobacterium marinum/efeitos dos fármacos; Mycobacterium marinum/crescimento & desenvolvimento; Fatores de Virulência/genética; Fatores de Virulência/metabolismo; Peixe-Zebra

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Ácidos Carboxílicos / Mycobacterium marinum / Viabilidade Microbiana / Lisossomos / Macrófagos / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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