[HPV-associated head and neck cancer: update and recommendations for practice]. / HPV-asociované karcinómy hlavy a krku: Aktualizácia poznatkov a odporúcania pre prax.
Cesk Patol
; 52(3): 130-8, 2016.
Article
em Cs
| MEDLINE
| ID: mdl-27526013
ABSTRACT
Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (HPV-OSCC) represents a specific clinical and pathological entity among head and neck cancers with more favorable prognosis than corresponding HPV-negative oropharyngeal squamous cell carcinoma (SCC). HPV-OSCC most commonly displays non-keratinzing SCC histology, although number of cases presented variable morphology. Detection of transcriptionally active HPV in oropharyngeal SCCs is of critical prognostic importance, which even supersedes the importance of their formal pathological grading. This article summarizes the current state of knowledge of HPV-positive SCC of oropharynx and of other anatomical subsites of the head and neck and discusses the role of HPV detection in the diagnostics of metastatic SCC lesions of unknown origin.
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Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Carcinoma de Células Escamosas
/
Infecções por Papillomavirus
/
Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
Cs
Ano de publicação:
2016
Tipo de documento:
Article