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Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti-PD-L1 Antibody Avelumab.
Khanna, Swati; Thomas, Anish; Abate-Daga, Daniel; Zhang, Jingli; Morrow, Betsy; Steinberg, Seth M; Orlandi, Augusto; Ferroni, Patrizia; Schlom, Jeffrey; Guadagni, Fiorella; Hassan, Raffit.
Afiliação
  • Khanna S; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Thomas A; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Abate-Daga D; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Zhang J; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Morrow B; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Steinberg SM; Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Orlandi A; Anatomic Pathology, Department of Biomedicine and Prevention, Tor Vergata University of Rome, Italy.
  • Ferroni P; San Raffaele Roma Open University and BioBIM (Interinstitutional Multidisciplinary BioBank), SR Research Center, IRCCS San Raffaele Pisana, Rome, Italy.
  • Schlom J; Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • Guadagni F; San Raffaele Roma Open University and BioBIM (Interinstitutional Multidisciplinary BioBank), SR Research Center, IRCCS San Raffaele Pisana, Rome, Italy.
  • Hassan R; Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: hassanr@mail.nih.gov.
J Thorac Oncol ; 11(11): 1993-2005, 2016 11.
Article em En | MEDLINE | ID: mdl-27544053
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígeno B7-H1 / Neoplasias Pulmonares / Mesotelioma / Anticorpos Monoclonais / Citotoxicidade Celular Dependente de Anticorpos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígeno B7-H1 / Neoplasias Pulmonares / Mesotelioma / Anticorpos Monoclonais / Citotoxicidade Celular Dependente de Anticorpos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article