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Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo.
Li, Haoyu; Wang, Yongfeng; Chen, Zhenghu; Lu, Jiaxiong; Pan, Jessie; Yu, Yang; Zhao, Yanling; Zhang, Huiyuan; Hu, Ting; Liu, Qing; Yang, Jianhua.
Afiliação
  • Li H; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.
  • Wang Y; The Institute of Skull Base Surgery and Neurooncology at Hunan Province, 410008, China.
  • Chen Z; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Lu J; Department of Microbiology, Peking University Health Science Center, Beijing 100191, China.
  • Pan J; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Yu Y; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Zhao Y; Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P. R. China.
  • Zhang H; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Hu T; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Liu Q; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Yang J; Texas Children's Cancer Center, Department of Pediatrics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.
Oncotarget ; 8(4): 5874-5884, 2017 Jan 24.
Article em En | MEDLINE | ID: mdl-27564113

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridazinas / Fator 2 de Crescimento de Fibroblastos / Inibidores de Proteínas Quinases / Receptor Tipo 1 de Fator de Crescimento de Fibroblastos / Imidazóis / Neuroblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridazinas / Fator 2 de Crescimento de Fibroblastos / Inibidores de Proteínas Quinases / Receptor Tipo 1 de Fator de Crescimento de Fibroblastos / Imidazóis / Neuroblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article