The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-&#945;ß/Î³ Receptor.

Koma, Takaaki; Huang, Cheng; Aronson, Judith F; Walker, Aida G; Miller, Milagros; Smith, Jeanon N; Patterson, Michael; Paessler, Slobodan

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αß/Î³ Receptor.

Koma, Takaaki; Huang, Cheng; Aronson, Judith F; Walker, Aida G; Miller, Milagros; Smith, Jeanon N; Patterson, Michael; Paessler, Slobodan.

Afiliação

Koma T; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Huang C; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Aronson JF; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Walker AG; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Miller M; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Smith JN; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Patterson M; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.
Paessler S; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.

PLoS Negl Trop Dis ; 10(8): e0004969, 2016 08.

Article em En | MEDLINE | ID: mdl-27580122

Assuntos

Vírus Junin/imunologia; Glicoproteínas de Membrana/imunologia; Receptores de Interferon/deficiência; Proteínas do Envelope Viral/imunologia; Vacinas Virais/imunologia; Células A549; Animais; Anticorpos Neutralizantes/sangue; Anticorpos Antivirais/sangue; Cricetinae; Modelos Animais de Doenças; Haplorrinos; Febre Hemorrágica Americana/prevenção & controle; Vírus Junin/patogenicidade; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Testes de Neutralização; Receptores de Interferon/genética; Proteínas Recombinantes/imunologia; Vacinas Atenuadas/imunologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Vacinas Virais / Proteínas do Envelope Viral / Receptores de Interferon / Vírus Junin Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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