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Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Wanek, Thomas; Kreis, Katharina; Krizková, Petra; Schweifer, Anna; Denk, Christoph; Stanek, Johann; Mairinger, Severin; Filip, Thomas; Sauberer, Michael; Edelhofer, Patricia; Traxl, Alexander; Muchitsch, Viktoria E; Mereiter, Kurt; Hammerschmidt, Friedrich; Cass, Carol E; Damaraju, Vijaya L; Langer, Oliver; Kuntner, Claudia.
Afiliação
  • Wanek T; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria. Electronic address: thomas.wanek@ait.ac.at.
  • Kreis K; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Krizková P; Institute of Organic Chemistry, University of Vienna, Währingerstraße 38, A-1090 Vienna, Austria.
  • Schweifer A; Institute of Organic Chemistry, University of Vienna, Währingerstraße 38, A-1090 Vienna, Austria.
  • Denk C; Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163, A-1060 Vienna, Austria.
  • Stanek J; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Mairinger S; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Filip T; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Sauberer M; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Edelhofer P; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Traxl A; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Muchitsch VE; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
  • Mereiter K; Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, A-1060 Vienna, Austria.
  • Hammerschmidt F; Institute of Organic Chemistry, University of Vienna, Währingerstraße 38, A-1090 Vienna, Austria.
  • Cass CE; Department of Oncology, University of Alberta, Edmonton, Alberta, Canada.
  • Damaraju VL; Department of Oncology, University of Alberta, Edmonton, Alberta, Canada.
  • Langer O; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
  • Kuntner C; Biomedical Systems, AIT Austrian Institute of Technology GmbH, A-2444 Seibersdorf, Austria.
Bioorg Med Chem ; 24(21): 5326-5339, 2016 11 01.
Article em En | MEDLINE | ID: mdl-27614920
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons / Imidazóis / Hipóxia / Monossacarídeos / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Radiofarmacêuticos / Tomografia por Emissão de Pósitrons / Imidazóis / Hipóxia / Monossacarídeos / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article