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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Ehret, Georg B; Ferreira, Teresa; Chasman, Daniel I; Jackson, Anne U; Schmidt, Ellen M; Johnson, Toby; Thorleifsson, Gudmar; Luan, Jian'an; Donnelly, Lousie A; Kanoni, Stavroula; Petersen, Ann-Kristin; Pihur, Vasyl; Strawbridge, Rona J; Shungin, Dmitry; Hughes, Maria F; Meirelles, Osorio; Kaakinen, Marika; Bouatia-Naji, Nabila; Kristiansson, Kati; Shah, Sonia; Kleber, Marcus E; Guo, Xiuqing; Lyytikäinen, Leo-Pekka; Fava, Cristiano; Eriksson, Niclas; Nolte, Ilja M; Magnusson, Patrik K; Salfati, Elias L; Rallidis, Loukianos S; Theusch, Elizabeth; Smith, Andrew J P; Folkersen, Lasse; Witkowska, Kate; Pers, Tune H; Joehanes, Roby; Kim, Stuart K; Lataniotis, Lazaros; Jansen, Rick; Johnson, Andrew D; Warren, Helen; Kim, Young Jin; Zhao, Wei; Wu, Ying; Tayo, Bamidele O; Bochud, Murielle; Absher, Devin; Adair, Linda S; Amin, Najaf; Arking, Dan E; Axelsson, Tomas.
Afiliação
  • Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Ferreira T; Cardiology, Department of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland.
  • Chasman DI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Jackson AU; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA.
  • Schmidt EM; Harvard Medical School, Boston, MA 02115, USA.
  • Johnson T; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Thorleifsson G; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Luan J; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Donnelly LA; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.
  • Kanoni S; GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK.
  • Petersen AK; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
  • Pihur V; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Strawbridge RJ; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.
  • Shungin D; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Hughes MF; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.
  • Meirelles O; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Kaakinen M; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Bouatia-Naji N; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.
  • Kristiansson K; Department of Public Health and Clinical Medicine, Umeå University, Sweden.
  • Shah S; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, SE-205 02 Malmö, Sweden.
  • Kleber ME; Department of Odontology, Umeå University, Sweden.
  • Guo X; Centre of Excellence for Public Health, Queens University Belfast, Grosvenor Road, Belfast BT126JP, UK.
  • Lyytikäinen LP; Laboratory of Genetics, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA.
  • Fava C; Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK.
  • Eriksson N; INSERM UMR970, Paris Cardiovascular Research Center PARCC, 56 rue Leblanc, 75015 Paris, France.
  • Nolte IM; University Paris-Descartes, Sorbonne Paris Cité, 12 rue de l'Ecole de medicine, F-75006 Paris, France.
  • Magnusson PK; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
  • Salfati EL; Institute for Molecular Medicine Finland FIMM, University of Helsinki, 00290 Helsinki, Finland.
  • Rallidis LS; Genetic Epidemiology Group, Dept. Epidemiology and Public Health, UCL, London, WC1E 6BT, UK.
  • Theusch E; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
  • Smith AJP; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA.
  • Folkersen L; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.
  • Witkowska K; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere 33014, Finland.
  • Pers TH; University of Lund, Dept Internal Medicine, Malmo, SE 20502, Sweden.
  • Joehanes R; University of Verona, Dept of Internal Medicine, Verona, Italy 37134.
  • Kim SK; Uppsala University, Uppsala Clinical Research Center, SE-75185 Uppsala, Sweden.
  • Lataniotis L; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Jansen R; Dept of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden.
  • Johnson AD; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Warren H; Second Department of Cardiology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece.
  • Kim YJ; Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA.
  • Zhao W; Department of Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London WC1E 6JF, UK.
  • Wu Y; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Tayo BO; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.
  • Bochud M; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK.
  • Absher D; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic, Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2100, Denmark.
  • Adair LS; Department of Epidemiology Research, Statens Serum Institut, 2300, Copenhagen, Denmark.
  • Amin N; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.
  • Arking DE; Dept. Dev. Bio. And Genetics, Stanford University Medical Center, Stanford, CA 94305, USA.
  • Axelsson T; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nat Genet ; 48(10): 1171-1184, 2016 10.
Article em En | MEDLINE | ID: mdl-27618452
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pressão Sanguínea Tipo de estudo: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pressão Sanguínea Tipo de estudo: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article