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Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer.
Moench, Romana; Grimmig, Tanja; Kannen, Vinicius; Tripathi, Sudipta; Faber, Marc; Moll, Eva-Maria; Chandraker, Anil; Lissner, Reinhard; Germer, Christoph-Thomas; Waaga-Gasser, Ana Maria; Gasser, Martin.
Afiliação
  • Moench R; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Grimmig T; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Kannen V; Ribeirao Preto Pharmaceutical Sciences School, Department of Toxicology, Bromatology, and Clinical Analysis, University of Sao Paulo, Sao Paulo, Brazil.
  • Tripathi S; Brigham and Women's Hospital, Transplant Research Center, Harvard Medical School, Boston, MA, USA.
  • Faber M; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Moll EM; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Chandraker A; Brigham and Women's Hospital, Transplant Research Center, Harvard Medical School, Boston, MA, USA.
  • Lissner R; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Germer CT; Department of Surgery I, University of Wuerzburg, Wuerzburg, Germany.
  • Waaga-Gasser AM; Department of Surgery I, Molecular Oncology and Immunology, University of Wuerzburg, Wuerzburg, Germany.
  • Gasser M; Brigham and Women's Hospital, Transplant Research Center, Harvard Medical School, Boston, MA, USA.
Oncotarget ; 7(42): 68749-68767, 2016 Oct 18.
Article em En | MEDLINE | ID: mdl-27626684
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Derivado de Plaquetas / Fosfatidilinositol 3-Quinases / Proliferação de Células / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Glicólise Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Derivado de Plaquetas / Fosfatidilinositol 3-Quinases / Proliferação de Células / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Glicólise Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article