Your browser doesn't support javascript.
loading
Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.
Santamaría Nuñez, Gema; Robles, Carlos Mario Genes; Giraudon, Christophe; Martínez-Leal, Juan Fernando; Compe, Emmanuel; Coin, Frédéric; Aviles, Pablo; Galmarini, Carlos María; Egly, Jean-Marc.
Afiliação
  • Santamaría Nuñez G; Cell Biology and Pharmacogenomics Department, Pharmamar SA, Colmenar Viejo, Madrid, Spain.
  • Robles CM; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, C. U. Strasbourg, France.
  • Giraudon C; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, C. U. Strasbourg, France.
  • Martínez-Leal JF; Cell Biology and Pharmacogenomics Department, Pharmamar SA, Colmenar Viejo, Madrid, Spain.
  • Compe E; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, C. U. Strasbourg, France.
  • Coin F; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, C. U. Strasbourg, France.
  • Aviles P; Cell Biology and Pharmacogenomics Department, Pharmamar SA, Colmenar Viejo, Madrid, Spain.
  • Galmarini CM; Cell Biology and Pharmacogenomics Department, Pharmamar SA, Colmenar Viejo, Madrid, Spain. cgalmarini@pharmamar.com.
  • Egly JM; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, C. U. Strasbourg, France.
Mol Cancer Ther ; 15(10): 2399-2412, 2016 10.
Article em En | MEDLINE | ID: mdl-27630271
Assuntos
Buscar no Google
Imprimir
XML
PubMed Links

Base de dados: MEDLINE Assunto principal: Produtos Biológicos / RNA Polimerase II / Quebras de DNA / Organismos Aquáticos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Buscar no Google
Imprimir
XML
PubMed Links

Base de dados: MEDLINE Assunto principal: Produtos Biológicos / RNA Polimerase II / Quebras de DNA / Organismos Aquáticos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article