Cytology smears as excellent starting material for next-generation sequencing-based molecular testing of patients with adenocarcinoma of the lung.

Velizheva, Nadezda P; Rechsteiner, Markus P; Wong, Christine E; Zhong, Qing; Rössle, Matthias; Bode, Beata; Moch, Holger; Soltermann, Alex; Wild, Peter J; Tischler, Verena

Velizheva, Nadezda P; Rechsteiner, Markus P; Wong, Christine E; Zhong, Qing; Rössle, Matthias; Bode, Beata; Moch, Holger; Soltermann, Alex; Wild, Peter J; Tischler, Verena.

Afiliação

Velizheva NP; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Rechsteiner MP; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Wong CE; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Zhong Q; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Rössle M; Cantonal Hospital Graubunden, Institute of Pathology, Chur, Switzerland.
Bode B; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Moch H; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Soltermann A; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Wild PJ; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.
Tischler V; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

Cancer Cytopathol ; 125(1): 30-40, 2017 Jan.

Article em En | MEDLINE | ID: mdl-27636102

Assuntos

Adenocarcinoma/diagnóstico; Citodiagnóstico; Sequenciamento de Nucleotídeos em Larga Escala; Neoplasias Pulmonares/diagnóstico; Manejo de Espécimes; Adenocarcinoma/genética; Adenocarcinoma/patologia; Adenocarcinoma de Pulmão; Feminino; Formaldeído; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Masculino; Mutação; Inclusão em Parafina; Proteínas Proto-Oncogênicas B-raf/genética; Proteínas Proto-Oncogênicas p21(ras)/genética

Palavras-chave

cell blocks; cytological smears; formalin-fixed, paraffin-embedded samples; lung adenocarcinoma; next-generation sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Manejo de Espécimes / Adenocarcinoma / Citodiagnóstico / Sequenciamento de Nucleotídeos em Larga Escala / Neoplasias Pulmonares Limite: Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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