Cognitive disorders and antiphospholipid antibodies.
Autoimmun Rev
; 15(12): 1193-1198, 2016 Dec.
Article
em En
| MEDLINE
| ID: mdl-27639839
ABSTRACT
Cognitive disorders have frequently been described in the field of antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Nevertheless, the relationship between those disorders and antiphospholipid antibodies (aPL) remains unclear and seems to involve various mechanisms. Overlap with systemic lupus erythematosus, the small sample size of studies, and discrepancies in antiphospholipid antibodies and cognitive impairment determinations complicate analyses of the literature data. In this paper, we summarize current knowledge on epidemiologic, clinical data, imaging findings and treatment of cognitive dysfunction associated with aPL. We separately analyzed data on aPL-positive carriers without history of clinical feature of APS, APS patients without overlaps autoimmune disease, and SLE-associated aPL patients.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Síndrome Antifosfolipídica
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Anticorpos Antifosfolipídeos
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Transtornos Cognitivos
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Lúpus Eritematoso Sistêmico
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article