The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.

Starrett, Gabriel J; Luengas, Elizabeth M; McCann, Jennifer L; Ebrahimi, Diako; Temiz, Nuri A; Love, Robin P; Feng, Yuqing; Adolph, Madison B; Chelico, Linda; Law, Emily K; Carpenter, Michael A; Harris, Reuben S

Starrett, Gabriel J; Luengas, Elizabeth M; McCann, Jennifer L; Ebrahimi, Diako; Temiz, Nuri A; Love, Robin P; Feng, Yuqing; Adolph, Madison B; Chelico, Linda; Law, Emily K; Carpenter, Michael A; Harris, Reuben S.

Afiliação

Starrett GJ; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Luengas EM; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
McCann JL; Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Ebrahimi D; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Temiz NA; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Love RP; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Feng Y; Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Adolph MB; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Chelico L; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Law EK; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Carpenter MA; Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Harris RS; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Nat Commun ; 7: 12918, 2016 09 21.

Article em En | MEDLINE | ID: mdl-27650891

Assuntos

Adenocarcinoma/metabolismo; Aminoidrolases/genética; Aminoidrolases/metabolismo; Neoplasias da Mama/genética; Predisposição Genética para Doença; Neoplasias Pulmonares/genética; Adenocarcinoma/genética; DNA/genética; Feminino; Haplótipos; Humanos; Mutação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Adenocarcinoma / Predisposição Genética para Doença / Aminoidrolases / Neoplasias Pulmonares Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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