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Modulating ryanodine receptors with dantrolene attenuates neuronopathic phenotype in Gaucher disease mice.
Liou, Benjamin; Peng, Yanyan; Li, Ronghua; Inskeep, Venette; Zhang, Wujuan; Quinn, Brian; Dasgupta, Nupur; Blackwood, Rachel; Setchell, Kenneth D R; Fleming, Sheila; Grabowski, Gregory A; Marshall, John; Sun, Ying.
Afiliação
  • Liou B; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Peng Y; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Li R; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Inskeep V; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Zhang W; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Quinn B; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Dasgupta N; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Blackwood R; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Setchell KD; Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Fleming S; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Grabowski GA; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio, USA.
  • Marshall J; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Sun Y; Sanofi Genzyme, Framingham, Massachusetts, USA.
Hum Mol Genet ; 25(23): 5126-5141, 2016 12 01.
Article em En | MEDLINE | ID: mdl-27655403
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canal de Liberação de Cálcio do Receptor de Rianodina / Dantroleno / Doença de Gaucher / Mitocôndrias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canal de Liberação de Cálcio do Receptor de Rianodina / Dantroleno / Doença de Gaucher / Mitocôndrias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article