Dioxin-like rather than non-dioxin-like PCBs promote the development of endometriosis through stimulation of endocrine-inflammation interactions.

Huang, Qiansheng; Chen, Yajie; Chen, Qionghua; Zhang, Huanteng; Lin, Yi; Zhu, Maobi; Dong, Sijun

Huang, Qiansheng; Chen, Yajie; Chen, Qionghua; Zhang, Huanteng; Lin, Yi; Zhu, Maobi; Dong, Sijun.

Afiliação

Huang Q; Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, People's Republic of China. qshuang@iue.ac.cn.
Chen Y; Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, People's Republic of China.
Chen Q; The First Affiliated Hospital of Xiamen University, Xiamen, 361003, People's Republic of China.
Zhang H; Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, People's Republic of China.
Lin Y; Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, People's Republic of China.
Zhu M; The First Affiliated Hospital of Xiamen University, Xiamen, 361003, People's Republic of China.
Dong S; Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, 361021, People's Republic of China. sjdong@iue.ac.cn.

Arch Toxicol ; 91(4): 1915-1924, 2017 Apr.

Article em En | MEDLINE | ID: mdl-27663891

Assuntos

Dioxinas e Compostos Semelhantes a Dioxinas/toxicidade; Endometriose/induzido quimicamente; Endométrio/efeitos dos fármacos; Bifenilos Policlorados/toxicidade; 17-Hidroxiesteroide Desidrogenases/metabolismo; Adulto; Animais; Células Cultivadas; Dioxinas e Compostos Semelhantes a Dioxinas/administração & dosagem; Relação Dose-Resposta a Droga; Endometriose/patologia; Endométrio/citologia; Estradiol/biossíntese; Feminino; Humanos; Inflamação/induzido quimicamente; Inflamação/patologia; Camundongos; Camundongos Endogâmicos BALB C; Pessoa de Meia-Idade; Bifenilos Policlorados/administração & dosagem; Receptores de Hidrocarboneto Arílico/metabolismo

Palavras-chave

Endometriosis; HSD17B7; LXA4; Methylation; Polychlorinated biphenyls

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bifenilos Policlorados / Endometriose / Endométrio / Dioxinas e Compostos Semelhantes a Dioxinas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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