Vitamin A prevents round spermatid nuclear damage and promotes the production of motile sperm during in vitro maturation of vitrified pre-pubertal mouse testicular tissue.

Dumont, L; Oblette, A; Rondanino, C; Jumeau, F; Bironneau, A; Liot, D; Duchesne, V; Wils, J; Rives, N

Dumont, L; Oblette, A; Rondanino, C; Jumeau, F; Bironneau, A; Liot, D; Duchesne, V; Wils, J; Rives, N.

Afiliação

Dumont L; EA 4308 'Gametogenesis and Gamete Quality', Reproductive Biology Laboratory-CECOS, Rouen University Hospital, Institute for Biomedical Research, Pavillon Derocque, Hôpital Charles Nicolle, 1 Rue de Germont, 76031 Rouen Cedex, France.
Oblette A; Normandy University, Ed 497 Normande de Biologie Intégrative, Santé et Environnement (EdNBISE), Bâtiment Principal UFR Sciences, Place Emilie Blondel, 76821 Mont-Saint-Aignan Cedex, France.
Rondanino C; Institute for Research and Innovation in Biomedicine (IRIB) , IRIB Normandy, 22 Boulevard Gambetta, 76183 Rouen Cedex, France.
Jumeau F; EA 4308 'Gametogenesis and Gamete Quality', Reproductive Biology Laboratory-CECOS, Rouen University Hospital, Institute for Biomedical Research, Pavillon Derocque, Hôpital Charles Nicolle, 1 Rue de Germont, 76031 Rouen Cedex, France.
Bironneau A; Normandy University, Ed 497 Normande de Biologie Intégrative, Santé et Environnement (EdNBISE), Bâtiment Principal UFR Sciences, Place Emilie Blondel, 76821 Mont-Saint-Aignan Cedex, France.
Liot D; Institute for Research and Innovation in Biomedicine (IRIB) , IRIB Normandy, 22 Boulevard Gambetta, 76183 Rouen Cedex, France.
Duchesne V; EA 4308 'Gametogenesis and Gamete Quality', Reproductive Biology Laboratory-CECOS, Rouen University Hospital, Institute for Biomedical Research, Pavillon Derocque, Hôpital Charles Nicolle, 1 Rue de Germont, 76031 Rouen Cedex, France.
Wils J; Institute for Research and Innovation in Biomedicine (IRIB) , IRIB Normandy, 22 Boulevard Gambetta, 76183 Rouen Cedex, France.
Rives N; EA 4308 'Gametogenesis and Gamete Quality', Reproductive Biology Laboratory-CECOS, Rouen University Hospital, Institute for Biomedical Research, Pavillon Derocque, Hôpital Charles Nicolle, 1 Rue de Germont, 76031 Rouen Cedex, France.

Mol Hum Reprod ; 22(12): 819-832, 2016 12.

Article em En | MEDLINE | ID: mdl-27671755

Assuntos

Espermátides/efeitos dos fármacos; Espermátides/metabolismo; Testículo/citologia; Vitamina A/farmacologia; Animais; Morte Celular/efeitos dos fármacos; Diferenciação Celular/efeitos dos fármacos; Criopreservação; Fragmentação do DNA/efeitos dos fármacos; Técnicas In Vitro; Masculino; Camundongos; Espermatogênese/efeitos dos fármacos; Espermatozoides/efeitos dos fármacos; Espermatozoides/metabolismo; Vitrificação

Palavras-chave

DNA fragmentation; animal model; cryopreservation; in vitro; retinol; spermatogenesis; testis; vitrification

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Base de dados: MEDLINE Assunto principal: Espermátides / Testículo / Vitamina A Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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