Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.

Hu, Jinchuan; Lieb, Jason D; Sancar, Aziz; Adar, Sheera

Hu, Jinchuan; Lieb, Jason D; Sancar, Aziz; Adar, Sheera.

Afiliação

Hu J; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7260.
Lieb JD; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Sancar A; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7260; aziz_sancar@med.unc.edu sheeraa@ekmd.huji.ac.il.
Adar S; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7260; aziz_sancar@med.unc.edu sheeraa@ekmd.huji.ac.il.

Proc Natl Acad Sci U S A ; 113(41): 11507-11512, 2016 10 11.

Article em En | MEDLINE | ID: mdl-27688757

Assuntos

Cisplatino/farmacologia; Dano ao DNA/genética; Genoma Humano; Nucleotídeos/genética; Sequência de Bases; Linhagem Celular; Reparo do DNA/efeitos dos fármacos; Reparo do DNA/genética; Humanos; Nucleossomos/metabolismo

Palavras-chave

Damage-seq; XR-seq; cancer; chemotherapy; nucleotide excision repair

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Genoma Humano / Cisplatino / Nucleotídeos Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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