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Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.
Bao, Lei; Chen, Shu-Jen; Conrad, Kathleen; Keefer, Kerry; Abraham, Thomas; Lee, John P; Wang, JuFang; Zhang, Xue-Qian; Hirschler-Laszkiewicz, Iwona; Wang, Hong-Gang; Dovat, Sinisa; Gans, Brian; Madesh, Muniswamy; Cheung, Joseph Y; Miller, Barbara A.
Afiliação
  • Bao L; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Chen SJ; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Conrad K; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Keefer K; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Abraham T; Neural and Behavioral Sciences and Microscopy Imaging Facility.
  • Lee JP; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Wang J; the Departments of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140; The Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
  • Zhang XQ; the Departments of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140; The Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
  • Hirschler-Laszkiewicz I; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Wang HG; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033; Departments of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Dovat S; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033; Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033 and.
  • Gans B; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033.
  • Madesh M; The Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140; Molecular Genetics and Medical Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
  • Cheung JY; the Departments of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140; The Center of Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
  • Miller BA; Departments of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033; Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033 and. Electronic address: bmiller3@psu.edu.
J Biol Chem ; 291(47): 24449-24464, 2016 Nov 18.
Article em En | MEDLINE | ID: mdl-27694440
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / Sinalização do Cálcio / Canais de Cátion TRPM / Glicólise / Mitocôndrias / Proteínas de Neoplasias / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / Sinalização do Cálcio / Canais de Cátion TRPM / Glicólise / Mitocôndrias / Proteínas de Neoplasias / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article