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Isolation of a natural cytotoxic IgM "antibody" in human serum sensitizing L cells to complement.
Bolande, R P; Mayer, D C.
Afiliação
  • Bolande RP; Department of Pathology, East Carolina University, School of Medicine, Greenville, North Carolina 27855.
Proc Soc Exp Biol Med ; 191(4): 387-90, 1989 Sep.
Article em En | MEDLINE | ID: mdl-2771965
ABSTRACT
An IgM fraction of human serum was isolated and purified. A portion of this fraction firmly attaches to L cells' surfaces, which sensitizes these cells to the lytic action of low concentrations of serum C. It contains the natural cytotoxic "antibody" to L cells.
Assuntos
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Base de dados: MEDLINE Assunto principal: Imunoglobulina M / Ativação do Complemento / Citotoxicidade Imunológica / Células L Limite: Animals / Female / Humans / Pregnancy Idioma: En Ano de publicação: 1989 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Imunoglobulina M / Ativação do Complemento / Citotoxicidade Imunológica / Células L Limite: Animals / Female / Humans / Pregnancy Idioma: En Ano de publicação: 1989 Tipo de documento: Article