Psychosocial distress and inflammation: Which way does causality flow?
Soc Sci Med
; 170: 1-8, 2016 12.
Article
em En
| MEDLINE
| ID: mdl-27728857
ABSTRACT
OBJECTIVES:
This study queried causal direction in linkages of inflammation with psychosocial distress.METHODS:
Data were from the 2005-2006 and 2010-2011 waves of the U.S. National Social Life, Health, and Aging Project. Inflammation was indicated by C-reactive protein, and distress by depression, anxiety, as well as stress. Autoregressive cross-lagged panel models were used to examine causal direction.RESULTS:
Rather than being an outcome of psychosocial distress, inflammation was a predictor of it. Linkages were gender differentiated, with inflammation seeming to induce depression among men but stress among women.DISCUSSION:
Contrary to previous literature, inflammation may not be a mechanism through which psychosocial distress gets "under the skin" to cause cardiovascular and metabolic issues. Rather, it may be a node through which social pathologies and life events influence both mental health and physiological problems.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
/
Causalidade
/
Inflamação
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article