Deciphering metal ion preference and primary coordination sphere robustness of a designed zinc finger with high-resolution mass spectrometry.

Laitaoja, Mikko; Isoniemi, Sari; Valjakka, Jarkko; Mándity, István M; Jänis, Janne

Laitaoja, Mikko; Isoniemi, Sari; Valjakka, Jarkko; Mándity, István M; Jänis, Janne.

Afiliação

Laitaoja M; Department of Chemistry, University of Eastern Finland, Joensuu, FI-80101, Finland.
Isoniemi S; Department of Chemistry, University of Eastern Finland, Joensuu, FI-80101, Finland.
Valjakka J; BioMediTech, University of Tampere, Tampere, FI-33520, Finland.
Mándity IM; Institute of Pharmaceutical Chemistry, University of Szeged, Szeged, H-6720, Hungary.
Jänis J; Department of Chemistry, University of Eastern Finland, Joensuu, FI-80101, Finland.

Protein Sci ; 26(2): 198-207, 2017 02.

Article em En | MEDLINE | ID: mdl-27750369

Assuntos

Modelos Moleculares; Dobramento de Proteína; Dedos de Zinco; Zinco/química; Substituição de Aminoácidos; Espectrometria de Massas; Mutação de Sentido Incorreto

Palavras-chave

mass spectrometry; metal ion binding; protein design; protein folding; zinc finger

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zinco / Modelos Moleculares / Dedos de Zinco / Dobramento de Proteína Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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