Recombinant protein of Haemonchus contortus 14-3-3 isoform 2 (rHcftt-2) decreased the production of IL-4 and suppressed the proliferation of goat PBMCs in vitro.

Gadahi, Javaid Ali; Ehsan, Muhammad; Wang, Shuai; Zhang, ZhenChao; Wang, Yujian; Yan, RuoFeng; Song, XiaoKai; Xu, LiXin; Li, XiangRui

Recombinant protein of Haemonchus contortus 14-3-3 isoform 2 (rHcftt-2) decreased the production of IL-4 and suppressed the proliferation of goat PBMCs in vitro.

Gadahi, Javaid Ali; Ehsan, Muhammad; Wang, Shuai; Zhang, ZhenChao; Wang, Yujian; Yan, RuoFeng; Song, XiaoKai; Xu, LiXin; Li, XiangRui.

Afiliação

Gadahi JA; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: drgadahi@yahoo.com.
Ehsan M; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: mehsan124@gmail.com.
Wang S; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: tongbaiws1003@163.com.
Zhang Z; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: zhangzhenchao525@163.com.
Wang Y; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: 453425665@qq.com.
Yan R; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: yanruofeng@njau.edu.cn.
Song X; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: songxiaokai@njau.edu.cn.
Xu L; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: xulixin@njau.edu.cn.
Li X; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China. Electronic address: lixiangrui@njau.edu.cn.

Exp Parasitol ; 171: 57-66, 2016 Dec.

Article em En | MEDLINE | ID: mdl-27751769

Assuntos

Haemonchus/imunologia; Proteínas de Helminto/imunologia; Interleucina-4/imunologia; Neutrófilos/imunologia; Proteínas Recombinantes/imunologia; Sequência de Aminoácidos; Animais; Anticorpos Anti-Helmínticos/biossíntese; Proliferação de Células/efeitos dos fármacos; Clonagem Molecular; DNA Complementar/metabolismo; DNA de Helmintos/metabolismo; Relação Dose-Resposta a Droga; Feminino; Cabras; Haemonchus/química; Haemonchus/genética; Proteínas de Helminto/química; Proteínas de Helminto/farmacologia; Interleucina-4/metabolismo; Neutrófilos/metabolismo; Óxido Nítrico/metabolismo; Filogenia; Reação em Cadeia da Polimerase; Isoformas de Proteínas/imunologia; Isoformas de Proteínas/farmacologia; RNA de Helmintos/genética; RNA de Helmintos/isolamento & purificação; Ratos; Ratos Sprague-Dawley; Proteínas Recombinantes/farmacologia; Alinhamento de Sequência

Palavras-chave

14-3-3 protein; Cytokine; Goat; Haemonchus contortus; PBMCs

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Proteínas de Helminto / Interleucina-4 / Haemonchus / Neutrófilos Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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