MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin.

Di Gregoli, Karina; Mohamad Anuar, Nur Najmi; Bianco, Rosaria; White, Stephen J; Newby, Andrew C; George, Sarah J; Johnson, Jason L

Di Gregoli, Karina; Mohamad Anuar, Nur Najmi; Bianco, Rosaria; White, Stephen J; Newby, Andrew C; George, Sarah J; Johnson, Jason L.

Afiliação

Di Gregoli K; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
Mohamad Anuar NN; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
Bianco R; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
White SJ; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
Newby AC; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
George SJ; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England.
Johnson JL; From the Laboratory of Cardiovascular Pathology, School of Clinical Sciences, University of Bristol, England. jason.l.johnson@bristol.ac.uk.

Circ Res ; 120(1): 49-65, 2017 Jan 06.

Article em En | MEDLINE | ID: mdl-27756793

Assuntos

Aneurisma da Aorta Abdominal/metabolismo; Aterosclerose/metabolismo; Elastina/fisiologia; MicroRNAs/biossíntese; Inibidor Tecidual de Metaloproteinase-3/fisiologia; Animais; Aneurisma da Aorta Abdominal/patologia; Aneurisma da Aorta Abdominal/prevenção & controle; Aterosclerose/patologia; Aterosclerose/prevenção & controle; Dieta Hiperlipídica/efeitos adversos; Elastina/antagonistas & inibidores; Feminino; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; MicroRNAs/antagonistas & inibidores; Pessoa de Meia-Idade; Inibidor Tecidual de Metaloproteinase-3/antagonistas & inibidores

Palavras-chave

aortic aneurysm, abdominal; atherosclerosis; macrophages; microRNAs; tissue inhibitor of metalloproteinase-3

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Elastina / Aneurisma da Aorta Abdominal / Inibidor Tecidual de Metaloproteinase-3 / MicroRNAs / Aterosclerose Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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