Concise SAR Exploration Based on the "Head-to-Tail" Approach: Discovery of PI4KIII&#945; Inhibitors Bearing Diverse Scaffolds.

Noji, Satoru; Seki, Noriyoshi; Maeba, Takaki; Sakai, Takayuki; Watanabe, Eiichi; Maeda, Katsuya; Fukushima, Kyoko; Noguchi, Toru; Ogawa, Kazuya; Toyonaga, Yukiyo; Negoro, Tamotsu; Kawasaki, Hisashi; Shiozaki, Makoto

Concise SAR Exploration Based on the "Head-to-Tail" Approach: Discovery of PI4KIIIα Inhibitors Bearing Diverse Scaffolds.

Noji, Satoru; Seki, Noriyoshi; Maeba, Takaki; Sakai, Takayuki; Watanabe, Eiichi; Maeda, Katsuya; Fukushima, Kyoko; Noguchi, Toru; Ogawa, Kazuya; Toyonaga, Yukiyo; Negoro, Tamotsu; Kawasaki, Hisashi; Shiozaki, Makoto.

Afiliação

Noji S; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Seki N; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Maeba T; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Sakai T; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Watanabe E; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Maeda K; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Fukushima K; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Noguchi T; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Ogawa K; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Toyonaga Y; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Negoro T; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Kawasaki H; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.
Shiozaki M; Chemical Research Laboratories, Biological Pharmacological Research Laboratories, and Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc. , 1-1, Murasaki-cho, Takatsuki, Osaka 569-1125, Japan.