Acoustic characterization of Thiel liver for magnetic resonance-guided focused ultrasound treatment.
Minim Invasive Ther Allied Technol
; 26(2): 92-96, 2017 Apr.
Article
em En
| MEDLINE
| ID: mdl-27784190
ABSTRACT
BACKGROUND:
The purpose of this work was to measure the essential acoustic parameters, i.e., acoustic impedance, reflection coefficient, attenuation coefficient, of Thiel embalmed human and animal liver. The Thiel embalmed tissue can be a promising, pre-clinical model to study liver treatment with Magnetic Resonance-guided Focused Ultrasound (MRgFUS). MATERIAL ANDMETHODS:
Using a single-element transducer and the contact pulse-echo method, the acoustic parameters, i.e., acoustic impedance, reflection coefficient and attenuation coefficient of Thiel embalmed human and animal liver were measured.RESULTS:
The Thiel embalmed livers had higher impedance, similar reflection and lower attenuation compared to the fresh tissue.CONCLUSIONS:
Embalming liver with Thiel fluid affects its acoustic properties. During MRgFUS sonication of a Thiel organ, more focused ultrasound (FUS) will be backscattered by the organ, and higher acoustic powers are required to reach coagulation levels (temperatures >56 °C).Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Imagem por Ressonância Magnética Intervencionista
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Ablação por Ultrassom Focalizado de Alta Intensidade
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Fígado
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Modelos Biológicos
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article