DrugCentral: online drug compendium.
Nucleic Acids Res
; 45(D1): D932-D939, 2017 01 04.
Article
em En
| MEDLINE
| ID: mdl-27789690
ABSTRACT
DrugCentral (http//drugcentral.org) is an open-access online drug compendium. DrugCentral integrates structure, bioactivity, regulatory, pharmacologic actions and indications for active pharmaceutical ingredients approved by FDA and other regulatory agencies. Monitoring of regulatory agencies for new drugs approvals ensures the resource is up-to-date. DrugCentral integrates content for active ingredients with pharmaceutical formulations, indexing drugs and drug label annotations, complementing similar resources available online. Its complementarity with other online resources is facilitated by cross referencing to external resources. At the molecular level, DrugCentral bridges drug-target interactions with pharmacological action and indications. The integration with FDA drug labels enables text mining applications for drug adverse events and clinical trial information. Chemical structure overlap between DrugCentral and five online drug resources, and the overlap between DrugCentral FDA-approved drugs and their presence in four different chemical collections, are discussed. DrugCentral can be accessed via the web application or downloaded in relational database format.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ferramenta de Busca
/
Bases de Dados de Produtos Farmacêuticos
/
Navegador
Tipo de estudo:
Clinical_trials
Limite:
Humans
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article