Herpes simplex virus ICP27 regulates alternative pre-mRNA polyadenylation and splicing in a sequence-dependent manner.

Tang, Shuang; Patel, Amita; Krause, Philip R

Tang, Shuang; Patel, Amita; Krause, Philip R.

Afiliação

Tang S; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993 philip.krause@fda.hhs.gov shuang.tang@fda.hhs.gov.
Patel A; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993.
Krause PR; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993 philip.krause@fda.hhs.gov shuang.tang@fda.hhs.gov.

Proc Natl Acad Sci U S A ; 113(43): 12256-12261, 2016 10 25.

Article em En | MEDLINE | ID: mdl-27791013

Assuntos

Processamento Alternativo/genética; Proteínas Imediatamente Precoces/genética; Simplexvirus/genética; Animais; Linhagem Celular; Chlorocebus aethiops; Humanos; Íntrons/genética; Poliadenilação/genética; Precursores de RNA/genética; Sítios de Splice de RNA/genética; Estabilidade de RNA/genética

Palavras-chave

DNA viruses; RNA 3' polyadenylation signals; alternative splicing; hostpathogen interactions; polyadenylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento Alternativo / Simplexvirus / Proteínas Imediatamente Precoces Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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