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F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.
Oliver, Jason D; Sibley, Graham E M; Beckmann, Nicola; Dobb, Katharine S; Slater, Martin J; McEntee, Laura; du Pré, Saskia; Livermore, Joanne; Bromley, Michael J; Wiederhold, Nathan P; Hope, William W; Kennedy, Anthony J; Law, Derek; Birch, Mike.
Afiliação
  • Oliver JD; F2G Ltd., Manchester M30 0LX, United Kingdom; joliver@f2g.com.
  • Sibley GEM; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Beckmann N; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Dobb KS; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Slater MJ; Cresset, Litlington SG8 0SS, United Kingdom.
  • McEntee L; Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GE, United Kingdom.
  • du Pré S; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Livermore J; Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GE, United Kingdom.
  • Bromley MJ; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Wiederhold NP; Fungus Testing Laboratory, Departments of Pathology and Medicine/Infectious Diseases, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Hope WW; Antimicrobial Pharmacodynamics and Therapeutics, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GE, United Kingdom.
  • Kennedy AJ; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Law D; F2G Ltd., Manchester M30 0LX, United Kingdom.
  • Birch M; F2G Ltd., Manchester M30 0LX, United Kingdom.
Proc Natl Acad Sci U S A ; 113(45): 12809-12814, 2016 Nov 08.
Article em En | MEDLINE | ID: mdl-27791100
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article