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The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Hu, Bo; Jin, Chengcheng; Li, Hua-Bing; Tong, Jiyu; Ouyang, Xinshou; Cetinbas, Naniye Malli; Zhu, Shu; Strowig, Till; Lam, Fred C; Zhao, Chen; Henao-Mejia, Jorge; Yilmaz, Omer; Fitzgerald, Katherine A; Eisenbarth, Stephanie C; Elinav, Eran; Flavell, Richard A.
Afiliação
  • Hu B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Jin C; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Li HB; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Tong J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Ouyang X; Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
  • Cetinbas NM; Section of Digestive Diseases, Yale University, New Haven, CT 06520, USA.
  • Zhu S; Koch Institute for Integrative Cancer Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA.
  • Strowig T; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Lam FC; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Zhao C; Koch Institute for Integrative Cancer Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA.
  • Henao-Mejia J; Hematology Oncology Fellowship Program, National Institutes of Health, Bethesda, MD 20892, USA.
  • Yilmaz O; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Fitzgerald KA; Koch Institute for Integrative Cancer Biology, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA.
  • Eisenbarth SC; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Elinav E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Flavell RA; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Science ; 354(6313): 765-768, 2016 11 11.
Article em En | MEDLINE | ID: mdl-27846608
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Apoptose / Proteínas de Ligação a DNA / Quebras de DNA de Cadeia Dupla / Inflamassomos Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lesões por Radiação / Apoptose / Proteínas de Ligação a DNA / Quebras de DNA de Cadeia Dupla / Inflamassomos Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article