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First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28.
Poirier, Nicolas; Blancho, Gilles; Hiance, Maryvonne; Mary, Caroline; Van Assche, Tim; Lempoels, Jos; Ramael, Steven; Wang, Weirong; Thepenier, Virginie; Braudeau, Cecile; Salabert, Nina; Josien, Regis; Anderson, Ian; Gourley, Ian; Soulillou, Jean-Paul; Coquoz, Didier; Vanhove, Bernard.
Afiliação
  • Poirier N; Institut National de la Santé et de la Recherche Médicale UMR 1064, Nantes F44093, France.
  • Blancho G; Institut de Transplantation Urologie Néphrologie, Centre Hospitalier Universitaire, Université de Nantes, Nantes F44000, France.
  • Hiance M; OSE Immunotherapeutics S.A., Nantes F44200, France.
  • Mary C; Institut National de la Santé et de la Recherche Médicale UMR 1064, Nantes F44093, France.
  • Van Assche T; Institut de Transplantation Urologie Néphrologie, Centre Hospitalier Universitaire, Université de Nantes, Nantes F44000, France.
  • Lempoels J; Centre Hospitalier Universitaire Nantes, Laboratoire d'Immunologie, Centre d'immunomonitorage Nantes-Atlantique, Nantes, F44000, France.
  • Ramael S; OSE Immunotherapeutics S.A., Nantes F44200, France.
  • Wang W; Institut National de la Santé et de la Recherche Médicale UMR 1064, Nantes F44093, France.
  • Thepenier V; Institut de Transplantation Urologie Néphrologie, Centre Hospitalier Universitaire, Université de Nantes, Nantes F44000, France.
  • Braudeau C; OSE Immunotherapeutics S.A., Nantes F44200, France.
  • Salabert N; SGS Life Science Services, Clinical Pharmacology Unit Antwerp, Antwerp 2060, Belgium.
  • Josien R; SGS Life Science Services, Clinical Pharmacology Unit Antwerp, Antwerp 2060, Belgium.
  • Anderson I; SGS Life Science Services, Clinical Pharmacology Unit Antwerp, Antwerp 2060, Belgium.
  • Gourley I; Janssen Research & Development, LLC, Spring House, PA 19477.
  • Soulillou JP; Institut National de la Santé et de la Recherche Médicale UMR 1064, Nantes F44093, France.
  • Coquoz D; Institut de Transplantation Urologie Néphrologie, Centre Hospitalier Universitaire, Université de Nantes, Nantes F44000, France.
  • Vanhove B; OSE Immunotherapeutics S.A., Nantes F44200, France.
J Immunol ; 197(12): 4593-4602, 2016 12 15.
Article em En | MEDLINE | ID: mdl-27849166
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Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Fragmentos Fab das Imunoglobulinas / Transplante de Órgãos / Rejeição de Enxerto / Imunoterapia / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Buscar no Google
Imprimir
XML
PubMed Links

Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Fragmentos Fab das Imunoglobulinas / Transplante de Órgãos / Rejeição de Enxerto / Imunoterapia / Anticorpos Monoclonais Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article