Effect of Pregnane X Receptor<sup>*</sup>1B genetic polymorphisms on postoperative analgesia with fentanyl in Chinese patients undergoing gynecological surgery.

Yuan, Jing-Jing; Ma, Xiao-Jing; Li, Zhi-Song; Chang, Yan-Zi; Zhang, Wei; Kan, Quan-Cheng; Hou, Jun-Kai; Zhang, Li-Rong

Effect of Pregnane X Receptor^*1B genetic polymorphisms on postoperative analgesia with fentanyl in Chinese patients undergoing gynecological surgery.

Yuan, Jing-Jing; Ma, Xiao-Jing; Li, Zhi-Song; Chang, Yan-Zi; Zhang, Wei; Kan, Quan-Cheng; Hou, Jun-Kai; Zhang, Li-Rong.

Afiliação

Yuan JJ; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.
Ma XJ; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.
Li ZS; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.
Chang YZ; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.
Zhang W; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China. zhangw571012@126.com.
Kan QC; Key Laboratory of Pharmacogenomics, No.1 East-JianShe Road, Zhengzhou, Henan Province, 450052, China.
Hou JK; First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.
Zhang LR; Department of Anesthesiology, First Affiliated Hospital of Zhengzhou University, No.1 East-JianShe Road, Zhengzhou, 450052, China.

BMC Med Genet ; 17(1): 87, 2016 Nov 23.

Article em En | MEDLINE | ID: mdl-27876007

Assuntos

Povo Asiático/genética; Fentanila/administração & dosagem; Dor Pós-Operatória/prevenção & controle; Receptores de Esteroides/genética; Adulto; Alelos; Analgesia Controlada pelo Paciente; China; Citocromo P-450 CYP3A/metabolismo; DNA/química; DNA/isolamento & purificação; DNA/metabolismo; Análise Mutacional de DNA; Feminino; Frequência do Gene; Genótipo; Procedimentos Cirúrgicos em Ginecologia; Haplótipos; Humanos; Pessoa de Meia-Idade; Polimorfismo de Nucleotídeo Único; Receptor de Pregnano X

Palavras-chave

Analgesia; CYP3A4; Fentanyl; Polymorphism; Pregnane X receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Receptores de Esteroides / Fentanila / Povo Asiático Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Middle aged País como assunto: Asia Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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