Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice.

Ong, Yong Sze; Saiful Yazan, Latifah; Ng, Wei Keat; Noordin, Mustapha M; Sapuan, Sarah; Foo, Jhi Biau; Tor, Yin Sim

Ong, Yong Sze; Saiful Yazan, Latifah; Ng, Wei Keat; Noordin, Mustapha M; Sapuan, Sarah; Foo, Jhi Biau; Tor, Yin Sim.

Afiliação

Ong YS; Laboratory of Molecular Biomedicine, Institute of Bioscience.
Saiful Yazan L; Laboratory of Molecular Biomedicine, Institute of Bioscience; Department of Biomedical Science, Faculty of Medicine and Health Sciences.
Ng WK; Laboratory of Molecular Biomedicine, Institute of Bioscience.
Noordin MM; Department of Pathology and Veterinary Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia.
Sapuan S; Laboratory of Molecular Biomedicine, Institute of Bioscience.
Foo JB; Laboratory of Molecular Biomedicine, Institute of Bioscience.
Tor YS; Laboratory of Molecular Biomedicine, Institute of Bioscience.

Int J Nanomedicine ; 11: 5905-5915, 2016.

Article em En | MEDLINE | ID: mdl-27877037

Assuntos

Benzoquinonas/química; Benzoquinonas/toxicidade; Lipídeos/química; Nanoestruturas/química; Animais; Benzoquinonas/farmacologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Composição de Medicamentos; Feminino; Humanos; Fígado/efeitos dos fármacos; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Nigella sativa/química; Sementes/química; Testes de Toxicidade Aguda

Palavras-chave

nanostructured lipid carrier; thymoquinone; toxicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoquinonas / Nanoestruturas / Lipídeos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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