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EMILIN3, an extracellular matrix molecule with restricted distribution in skin.
Corallo, Diana; Schiavinato, Alvise; Bizzotto, Dario; Milanetto, Martina; Guljelmovic, Marija; Keene, Douglas R; Sengle, Gerhard; Braghetta, Paola; Bonaldo, Paolo.
Afiliação
  • Corallo D; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Schiavinato A; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Bizzotto D; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Milanetto M; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Guljelmovic M; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Keene DR; Shriners Hospital for Children, Portland, OR, USA.
  • Sengle G; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
  • Braghetta P; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Bonaldo P; Department of Molecular Medicine, University of Padova, Padova, Italy.
Exp Dermatol ; 26(5): 435-438, 2017 05.
Article em En | MEDLINE | ID: mdl-27892605
ABSTRACT
EMILIN3 is an extracellular matrix glycoprotein that displays a dynamic and restricted expression pattern in connective tissues during post-natal life. In this study, we report the characterization of EMILIN3 deposition in the skin. In addition, to unravel the functions of this protein in skin homeostasis, we generated Emilin3 null mice and provide evidence that EMILIN3 is dispensable for hair follicle growth and maintenance throughout adult life.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas / Proteínas da Matriz Extracelular / Folículo Piloso Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas / Proteínas da Matriz Extracelular / Folículo Piloso Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article